BPC-157

BPC-157

BPC-157 is a synthetic pentadecapeptide, a chain of 15 amino acids, derived from a sequence found in a protein in gastric juice (“body protection compound”). It is one of the most widely studied research peptides in preclinical literature, with a large body of rodent and cell-culture work published since the early 1990s.

Product Specifications

• Product: BPC-157
• Amount: See available options above
• Form: Lyophilized powder
• Purity: Third-party tested by an ISO 17025 U.S. laboratory. See the batch Certificate of Analysis (COA) on this page.
• Storage: Keep sealed and refrigerated at 2–8°C (36–46°F), protected from light.
• Ships from: United States, 2-day UPS

Chemical Profile

• Compound class: Synthetic pentadecapeptide
• Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (15 residues)
• Molecular formula: C₆₂H₉₈N₁₆O₂₂
• Molecular weight: 1419.5 g/mol
• CAS number: 137525-51-0

What researchers study

Most published BPC-157 research comes from animal and in-vitro models. Areas of investigation include:

• Tendon and fibroblast biology: rat Achilles tendon explants and cultured tendon fibroblasts, looking at outgrowth, cell survival under oxidative stress, cell migration, and FAK-paxillin signaling.
• Blood vessels and angiogenesis: animal vascular-injury models and endothelial cell (HUVEC) assays measuring proliferation, migration and tube formation, with attention to nitric oxide and VEGF pathways.
• Gut-brain axis: rodent studies of the gastrointestinal tract and its links to serotonin and dopamine systems.
• Wound models: alkali-burn and other tissue-injury models in rats.

A 2025 systematic review of the musculoskeletal literature found that the evidence is almost entirely preclinical and reported that no clinical safety data were found. Results from animal and cell models do not establish effects in humans.

Regulatory status

BPC-157 is not approved by the FDA for any use. It has been on the World Anti-Doping Agency’s Prohibited List under S0 (non-approved substances) since 2022. It is sold here as a research reagent only.

Quality & Documentation

Every batch of BPC-157 is made in small runs for Rogue Compounds and tested by an independent U.S. laboratory for identity (mass spectrometry) and purity (HPLC). Each vial is labeled with its batch number and a QR code that opens the testing lab’s own report for that batch. The same batch Certificate of Analysis is posted on this page and in our COA Library, so you can check one against the other.

Research overview

For a longer look at BPC-157, covering where it came from, what cell and animal studies have measured, and what the evidence does not show, read our BPC-157 research overview. It is written as background reading, and every study it cites is linked to PubMed.

Selected literature

• Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011;110(3):774-780. PMID 21030672
• Seiwerth S, et al. BPC 157 and blood vessels. Curr Pharm Des. 2014;20(7):1121-1125. PMID 23782145
• Huang T, et al. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015;9:2485-2499. PMID 25995620
• Sikiric P, et al. Brain-gut axis and pentadecapeptide BPC 157: theoretical and practical implications. Curr Neuropharmacol. 2016;14(8):857-865. PMID 27138887
• Vasireddi N, et al. Emerging use of BPC-157 in orthopaedic sports medicine: a systematic review. HSS J. 2025;21(4):485-495. PMID 40756949

Research Use Only

This product is sold strictly as a research chemical for in-vitro laboratory and analytical use by qualified professionals. It is not a drug, dietary supplement, food, or cosmetic, and it is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary use. Rogue Compounds does not provide dosing, preparation, or usage instructions. The literature on this page is listed for scientific background only and does not describe this product or any use of it.