Acetic Acid Solution
Acetic Acid Solution is a dilute aqueous solution of acetic acid, the simplest carboxylic acid after formic acid, supplied as a laboratory reagent in a sealed 10ml vial. Dilute acetic acid is a standard solvent and diluent in peptide and protein laboratories, used to dissolve lyophilized research materials that are poorly soluble in neutral water.
Product Specifications
- Product: Acetic Acid Solution
- Amount: 10ml vial
- Form: Liquid solution, 10ml vial
- Purity: Third-party tested by an ISO 17025 U.S. laboratory. See the batch Certificate of Analysis (COA) on this page.
- Storage: Keep sealed at room temperature, protected from light.
- Ships from: United States, 2-day UPS
Chemical Profile
- Compound class: Carboxylic acid (dilute aqueous solution)
- Active component: Acetic acid (ethanoic acid), CH3COOH
- Molecular formula: C2H4O2
- Molecular weight: 60.05 g/mol
- CAS number: 64-19-7
- Solvent: Water
- Concentration: 0.6% acetic acid
Laboratory role
Acetic acid is a weak acid with a pKa of about 4.76. In dilute solution it lowers the pH enough to protonate basic side chains (lysine, arginine, histidine) and the N-terminal amine of a peptide, giving the molecule a net positive charge. That added charge often helps basic or aggregation-prone peptides go into solution when water alone is not enough. Because acetic acid is volatile, it can be removed by lyophilization, and it is compatible with the acetate counter-ion that many synthetic peptides already carry after purification.
Common laboratory uses include:
- Dissolving lyophilized peptides and proteins for in-vitro assays and analytical work.
- Preparing stock solutions that are later diluted into an assay buffer.
- Acidifying samples and mobile phases in chromatography and mass spectrometry workflows.
The right solvent for any given material depends on its sequence, charge and the downstream assay, and should be confirmed by the researcher.
Sterility & handling
The solution is filled into sealed vials for laboratory use. Handle it with standard aseptic technique and appropriate personal protective equipment, and keep the vial closed when not in use to prevent contamination and evaporation. Dilute acetic acid is a mild irritant to eyes and skin; refer to the safety data for acetic acid for handling and disposal.
Regulatory status
Acetic Acid Solution is a laboratory reagent. It is not a drug, is not FDA-approved for any use, and is not for human or veterinary use.
Quality & Documentation
Every batch of Acetic Acid Solution is made in small runs for Rogue Compounds and tested by an independent U.S. laboratory for identity and concentration. Each vial is labeled with its batch number and a QR code that opens the testing lab’s own report for that batch. The same batch Certificate of Analysis is posted on this page and in our COA Library, so you can check one against the other.
Research Use Only
This product is sold strictly as a research chemical for in-vitro laboratory and analytical use by qualified professionals. It is not a drug, dietary supplement, food, or cosmetic, and it is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary use. Rogue Compounds does not provide dosing, preparation, or usage instructions. The literature on this page is listed for scientific background only and does not describe this product or any use of it.
