Name: IGF-DES
SKU: 4959
Price: 100.00 USD
Availability: OutOfStock

Research Overview

Age Requirement: All customers must be at least 21 years of age.
Product Use: All products are sold for in-vitro research applications only. They are not for human or animal consumption, cosmetic use, or as dietary supplements.
No Medical Advice: We are not a pharmacy or medical provider. We do not provide medical advice, dosing instructions, or reconstitution guidance for human use.
Compliance: It is the researcher’s responsibility to handle all materials in accordance with their institution’s safety protocols and all applicable local, state, and federal laws.
Sales Are Final: Due to the nature of these materials, all sales are final. We do not accept returns or exchanges. Please review our Shipping &amp; Returns policy for handling damaged items or shipping issues.

IGF-DES (IGF-1 DES 1-3) is a truncated analogue of insulin-like growth factor-1 studied in research models involving IGF-1 receptor signaling, cellular proliferation, tissue regeneration, skeletal muscle physiology, and growth factor biology.

Produced by removing the first three amino acids of native IGF-1, IGF-DES exhibits altered receptor interactions and reduced affinity for insulin-like growth factor binding proteins (IGFBPs). These characteristics have established it as an important research tool for investigating localized IGF-1 signaling and the molecular mechanisms that regulate cellular growth and tissue remodeling.

Lyophilized Vial Format

Precision-manufactured and lyophilized for stability, this research-grade peptide is produced to support reproducible laboratory workflows requiring accurate preparation, controlled storage, and consistent experimental performance.

Why Researchers Study IGF-DES

IGF-DES is investigated for its interaction with the insulin-like growth factor-1 receptor (IGF-1R), a signaling pathway that plays a central role in cellular growth, differentiation, and tissue maintenance. Its modified structure and reduced binding to IGF-binding proteins allow researchers to examine localized IGF signaling with fewer regulatory constraints than native IGF-1.

Its distinct pharmacological profile has made IGF-DES a valuable research peptide for studying growth factor biology, regenerative processes, skeletal muscle physiology, and the complex signaling networks that coordinate cellular adaptation and tissue homeostasis.